Biomedical Illustration

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Hypertrophic Scarring Editorial Spread

Clients: Dr. Shelley Wall

 

Medium: Adobe Photoshop and Illustrator

Audience: Scientific American readers

Date: December 2018

Project Details: COMING SOON

 

Process Work

References

Cheng, W., Yan-hua, R., Fang-gang, N., & Guo-an, Z. (2010). The content and ratio of type I and III collagen in skin differ with age and injury. African Journal of Biotechnology, 9(28), 4482–4485. https://doi.org/10.5897/AJB10.1999

Ghazawi, F. M., Zargham, R., Gilardino, M. S., Sasseville, D., & Jafarian, F. (2018). Insights into the Pathophysiology of Hypertrophic Scars and Keloids. Advances in Skin & Wound Care, 31(1), 582–595. https://doi.org/10.1097/01.ASW.0000527576.27489.0f

Lyder, C. H., & Ayello, E. A. (2009). Actividade E X Tra. Advances in Skin & Wound Care, 22(10), 476–484.

Ogawa, R., & Akaishi, S. (2016). Endothelial dysfunction may play a key role in keloid and hypertrophic scar pathogenesis – Keloids and hypertrophic scars may be vascular disorders. Medical Hypotheses, 96, 51–60. https://doi.org/10.1016/j.mehy.2016.09.024

Ogawa, R. (2017). Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis. International Journal of Molecular Sciences, 18(3). https://doi.org/10.3390/ijms18030606

Son, D., & Harijan, A. (2014). Overview of surgical scar prevention and management. Journal of Korean Medical Science, 29(6), 751–757. https://doi.org/10.3346/jkms.2014.29.6.751

Suarez, E., Syed, F., Alonso-Rasgado, T., & Bayat, A. (2015). Identification of biomarkers involved in differential profiling of hypertrophic and keloid scars versus normal skin. Archives of Dermatological Research, 307(2), 115–133. https://doi.org/10.1007/s00403-014-1512-4

Thorne,C.H. (2013). Grabb and Smith’s Plastic Surgery. 7th ed. Wolters Kluwer Health, Overview, C. (n.d.). Plastic surgery, 209–224.

Tziotzios, C., Profyris, C., & Sterling, J. (2012). Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics: Part II. Strategies to reduce scar formation after dermatologic procedures. Journal of the American Academy of Dermatology, 66(1), 13–24. https://doi.org/10.1016/j.jaad.2011.08.035

Wolfram, D., Tzankov, A., Pülzl, P., & Piza-Katzer, H. (2009). Hypertrophic scars and keloids - A review of their pathophysiology, risk factors, and therapeutic management. Dermatologic Surgery, 35(2), 171–181. https://doi.org/10.1111/j.1524-4725.2008.34406.x

Xue, M., & Jackson, C. J. (2015). Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring. Advances in Wound Care, 4(3), 119–136. https://doi.org/10.1089/wound.2013.0485

Yoo, M. G., & Kim, I. H. (2014). Keloids and hypertrophic scars: Characteristic vascular structures visualized by using dermoscopy. Annals of Dermatology, 26(5), 603–609. https://doi.org/10.5021/ad.2014.26.5.603

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Tissue Cube Studies

Initial Layout Sketches and Colour Studies

Illustration Assets

Rachael Whitehead 2020 ©