Biomedical Illustration

Hypertrophic Scarring Editorial Spread

Clients: Dr. Shelley Wall

Medium: Adobe Photoshop and Illustrator

Audience: Scientific American readers

Date: December 2018


Cheng, W., Yan-hua, R., Fang-gang, N., & Guo-an, Z. (2010). The content and ratio of type I and III collagen in skin differ with age and injury. African Journal of Biotechnology, 9(28), 4482–4485.

Ghazawi, F. M., Zargham, R., Gilardino, M. S., Sasseville, D., & Jafarian, F. (2018). Insights into the Pathophysiology of Hypertrophic Scars and Keloids. Advances in Skin & Wound Care, 31(1), 582–595.

Lyder, C. H., & Ayello, E. A. (2009). Actividade E X Tra. Advances in Skin & Wound Care, 22(10), 476–484.

Ogawa, R., & Akaishi, S. (2016). Endothelial dysfunction may play a key role in keloid and hypertrophic scar pathogenesis – Keloids and hypertrophic scars may be vascular disorders. Medical Hypotheses, 96, 51–60.

Ogawa, R. (2017). Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis. International Journal of Molecular Sciences, 18(3).

Son, D., & Harijan, A. (2014). Overview of surgical scar prevention and management. Journal of Korean Medical Science, 29(6), 751–757.

Suarez, E., Syed, F., Alonso-Rasgado, T., & Bayat, A. (2015). Identification of biomarkers involved in differential profiling of hypertrophic and keloid scars versus normal skin. Archives of Dermatological Research, 307(2), 115–133.

Thorne,C.H. (2013). Grabb and Smith’s Plastic Surgery. 7th ed. Wolters Kluwer Health, Overview, C. (n.d.). Plastic surgery, 209–224.

Tziotzios, C., Profyris, C., & Sterling, J. (2012). Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics: Part II. Strategies to reduce scar formation after dermatologic procedures. Journal of the American Academy of Dermatology, 66(1), 13–24.

Wolfram, D., Tzankov, A., Pülzl, P., & Piza-Katzer, H. (2009). Hypertrophic scars and keloids - A review of their pathophysiology, risk factors, and therapeutic management. Dermatologic Surgery, 35(2), 171–181.

Xue, M., & Jackson, C. J. (2015). Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring. Advances in Wound Care, 4(3), 119–136.

Yoo, M. G., & Kim, I. H. (2014). Keloids and hypertrophic scars: Characteristic vascular structures visualized by using dermoscopy. Annals of Dermatology, 26(5), 603–609.

Rachael Whitehead 2020 ©